What Is It?
Low-dose naltrexone (LDN) is gaining attention for its potential to support weight loss. By reducing inflammation and insulin levels, it can help decrease hunger and cravings. It’s often prescribed for those with a BMI of 24 and above.
Studies have shown that LDN may lead to reduced appetite, make food less tempting, and support gradual weight loss. For example, one study reported weight loss of up to 7.5 pounds in patients using naltrexone.
At higher doses, naltrexone is used to treat alcohol and opioid use disorders, but in lower doses, its effects on weight and inflammation make it a versatile option.
Dosage and Administration
For specific dosing information, please consult your clinician.
Benefits:
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May reduce inflammation
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Supports weight loss
When Not to Use Naltrexone:
Naltrexone should not be used if you are:
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Currently taking opioids or in withdrawal
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Allergic to the medication
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Pregnant, breastfeeding, or have liver disease
Avoid taking naltrexone with the following medications:
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Dextromethorphan
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Certain diarrhea medications (like loperamide)
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Disulfiram
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Opioid pain or cough medications (e.g., codeine, hycodan)
Side Effects That May Occur
Possible Side Effects****
You may experience side effects, such as:
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Nausea
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Sleepiness
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Headache
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Dizziness
Rarely, serious side effects may occur, such as:
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Severe injection reactions
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Liver issues
If anything unusual comes up, it's always best to check with your clinician.